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Pharmacogenomics An Introduction and Clinical Perspective de Joseph Bertino,Angela Kashuba,Joseph Ma,C. Lindsay Devane,Uwe Fuhr

Descripción - Reseña del editor A COMPLETE INTRODUCTORY TEXT TO THE FIELD OF PHARMACOGENOMICSA Doody's Core Title for 2017!The only pharmacogenomics resource to feature a global author team comprised of PharmDs, MDs, PhDs and social scientists, Pharmacogenomics offers an essential, highly accessible survey of this dynamic discipline. You will find thorough coverage of all need-to-know topics, from individual molecules to systemic diseases, plus anexamination of the latest technologies that are constantly reshaping the field. Pharmacogenomics is cohesively organized into two sections, the first of which reviewsbasic aspects of pharmacogenomics, including ethics, regulatory, science, and drug metabolism, along with a 'mini' course in molecular genetics and testing. The second section highlights the practical application of pharmacogenomics in cardiovascular medicine, immunology, neurology, and other specialties.FEATURESImportant overview of general pharmacogenomics and pharmacogenetics concepts, including geneticvariation in signal transduction and targets, plus a review of the genetic concepts of pharmacogenomicsDiscussion of regulatory considerations in pharmacogenomicsFocus on the role of health care professionals along with a review of related privacy issues,as well as broader ethical, legal, and social considerationsIn-depth chapters on drug metabolism and transportersPractical, step-by-step guidance on public access to pharmacogenomic testing and patient counselingUp-to-date coverage of non-genetic influences on pharmacogenomicsEmphasis on gene-drug interactionsNumerous tables and figuresChapter-ending referencesConcise learning objectives at the beginning of each chapterCase studies to familiarize you with the clinical relevance of pharmacogenomics in each specialty Biografía del autor Joseph S. Bertino Jr., Pharm.D. is an Associate Professor of Clinical Pharmacology in Medicine at the College of Physicians and Surgeons, Columbia University, New York, NY. His research interests are varied and include work with vaccines, antimicrobial pharmacokinetics and pharmacodynamics, treatment of hypertension, pharmacogenetics and pharmacogenomics. Dr. Bertino received the Pharm.D. degree from SUNY at Buffalo. He has published over 100 original research papers, review articles and book chapters. His publications have included work in the area of antimicrobial pharmacokinetics, pharmacodynamics and toxicity, drug-drug interactions, general clinical pharmacology, vaccine pharmacology and the application of pharmacogenetics to the drug development process. Joseph D. Ma, PharmD is an Assistant Professor at the University of California San Diego, Skaggs School of Pharmacy and Pharmaceutical Sciences. He received his Pharmacy Doctorate from the University of California, San Francisco. He then completed a 2-year fellowship in clinical pharmacology at Bassett Healthcare, Cooperstown, NY. Upon fellowship completion, Dr. Ma was employed at Amgen, Inc. and was responsible for phase I protocol development and study operational and managerial functions. Dr. Ma joined UCSD in 2007. He serves as co-coordinator for the winter quarter Therapeutics course and for a spring quarter elective titled Drug Discovery, Development, and Commercialization. His research interests are in examining pharmacokinetic and pharmacodynamic variability and in the optimization of drugs as probes to phenotype drug-metabolizing enzyme activity. Angela Kashuba, PharmD is an Associate Professor of Pharmacy at the University of North Carolina in Chappel Hill. Ms. Kashuba received two grants specifically on pharmcgenomics on the elderly. C. Lindsay DeVane, Pharm.D. is Professor of Psychiatry and Behavioral Sciences and Vice Chair for Research in the Department of Psychiatry at the Medical University of South Carolina (MUSC) in Charleston, SC. He directs the Laboratory of Drug Disposition and Pharmacogenetics in the Darby Children's Research Institute and oversees operation of the core laboratories of MUSC's General Clinical Research Center. Professor Uwe Fuhr MD, is Clinical Pharmacologist at University of Cologne, Cologne, Germany, Faculty of Medicine. He is a native of Saarbruecken, Germany, and attended Johann Wolfgang Goethe University in Frankfurt am Main, Germany, as an undergraduate in Medicine where he obtained state registration as a physician in 1987.

Detalles del Libro

  • Name: Pharmacogenomics An Introduction and Clinical Perspective
  • Autor: Joseph Bertino,Angela Kashuba,Joseph Ma,C. Lindsay Devane,Uwe Fuhr
  • Categoria: Libros,Libros universitarios y de estudios superiores,Medicina y ciencias de la salud
  • Tamaño del archivo: 10 MB
  • Tipos de archivo: PDF Document
  • Descargada: 253 times
  • Idioma: Español
  • Archivos de estado: AVAILABLE


Lee un libro Pharmacogenomics An Introduction and Clinical Perspective de Joseph Bertino,Angela Kashuba,Joseph Ma,C. Lindsay Devane,Uwe Fuhr Libros Gratis en EPUB

Pharmacogenomics An Introduction and Clinical Perspective ~ Pharmacogenomics An Introduction and Clinical Perspective 1st Edition by Joseph Bertino (Author), Angela Kashuba (Author), Joseph Ma (Author), & 4.8 out of 5 stars 7 ratings. ISBN-13: 978-0071741699. ISBN-10: 0071741690. Why is ISBN important? ISBN. This bar-code number .

Pharmacogenomics An Introduction and Clinical Perspective ~ Pharmacogenomics An Introduction and Clinical Perspective (English Edition) eBook: Bertino, Joseph S., Kashuba, Angela, Ma, Joseph D., Fuhr, Uwe, DeVane, C. Lindsay .

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Pharmacogenomics in the clinic - PubMed Central (PMC) ~ Introduction. Pharmacogenomics focuses on the identification of genome variants that influence drug effects, typically via alterations in a drug’s pharmacokinetics (i.e., absorption, distribution, metabolism, elimination) or via modulation of a drug’s pharmacodynamics (e.g., modifying a drug’s target or perturbing biological pathways that alter sensitivity to the drug’s pharmacological .

Pharmacogenomics An Introduction and Clinical Perspective ~ Pharmacogenomics An Introduction and Clinical Perspective A COMPLETE INTRODUCTORY TEXT TO THE FIELD OF PHARMACOGENOMICS. The only pharmacogenomics resource to feature a global author team comprised of PharmDs, MDs, PhDs and social scientists, Pharmacogenomics offers an essential, highly accessible survey of this dynamic discipline. Medical books Pharmacogenomics An Introduction and Clinical .

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Clinical pharmacogenomics: patient perspectives of ~ 1. Per Med. 2017 Sep;14(5):383-388. doi: 10.2217/pme-2017-0022. Epub 2017 Sep 1. Clinical pharmacogenomics: patient perspectives of pharmacogenomic testing and the incidence of actionable test results in a chronic disease cohort.

Pharmacogenomics An Introduction and Clinical Perspective ~ Pris: 719 kr. Häftad, 2012. Skickas inom 7-10 vardagar. Köp Pharmacogenomics An Introduction and Clinical Perspective av Joseph Bertino på Bokus.

Pharmacogenomics An Introduction and Clinical Perspective ~ Pharmacogenomics An Introduction and Clinical Perspective A COMPLETE INTRODUCTORY TEXT TO THE FIELD OF PHARMACOGENOMICS The only pharmacogenomics resource to feature a global author team comprised of PharmDs, MDs, PhDs and social scientists, Pharmacogenomics offers an essential, highly accessible survey of this dynamic discipline. You will find thorough coverage of all need-to-know topics .

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Pharmacogenomics - 1st Edition ~ Pharmacogenomics: Challenges and Opportunities in Therapeutic Implementation includes discussions and viewpoints from the academic, regulatory, pharmaceutical, clinical, socio-ethical and economic perspectives. Each chapter presents an overview of the potential or opportunity within the areas discussed and also outlines foreseeable challenges and limitations in moving pharmacogenomics into .

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Global Pharmacogenomics Within Precision Medicine ~ Challenge 1: There is No Global Network of Experts to Help Drive Basic Pharmacogenomics Research and Clinical Implementation. The creation of a unified network comprised of researchers, clinicians, patients, and professionals from academia, government, and industry would increase the visibility and relevance of pharmacogenomics within the genomics and implementation science communities.

AN INTRODUCTION TO PHARMACOGENOMICS ~ AN INTRODUCTION TO PHARMACOGENOMICS Ashim Malhotra P GLYCOPROTEIN, 111 CLINICAL IMPLICATIONS OF PHARMACOGENOMICS, 111 Adverse Drug Reactions Warfarin Pharmacogenetic Testing Prior to Prescribing SUMMARY, 113 A dvances in health care have led to a significant improve-ment in patient survival in the past three decades. The

The Impact of Pharmacogenomics on Drug Development ~ Report 2 - Free download as Word Doc (.doc), PDF File (.pdf), Text File (.txt) or read online for free.

Pharmacogenomics / Vol 21, No 8 ~ Pharmacogenomics welcomes unsolicited article proposals. . Cost–effectiveness of combinatorial pharmacogenomic testing for depression from the Canadian public payer perspective. Julie-Anne Tanner, Paige E Davies, Christopher C Overall, Daniel Grima . The clinical utility of combinatorial pharmacogenomic testing for patients with .

(PDF) Introduction To Pharmacogenomics - ResearchGate ~ PDF / On Jun 1, 2007, Vicki L. Ellingrod and others published Introduction To Pharmacogenomics / Find, read and cite all the research you need on ResearchGate

Pharmacogenomics: a key component of personalized therapy ~ Several important applications of pharmacogenomics are already being used in clinical practice and some of them have been approved by the FDA (for example, cetuximab/panitumumab and KRAS; vemurafenib and BRAF; warfarin and CYP2C9/VKORC1; abacavir and HLA-B*5701; carbamazepin and HLA-B*1502; thiopurines and TPMT) [].Other candidates have been identified (for example, tamoxifen []), but their .

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Pharmacogenomics Principles: Introduction to Personalized ~ Pharmacogenomics Principles: Introduction to Personalized Medicine. Parvaz Madadi. Division of Clinical Pharmacology and Toxicology, Hospital for Sick Children, Toronto, Canada. Search for more papers by this author. Gideon Koren.

Pharmacogenomics - LinkedIn SlideShare ~ Pharmacogenomics 1. SIRISHAANNAVARAPU DEPT OF PHARMACOLOGY, KIMS 2. Introduction • Pharmacogenomics deals with the influence of genetic variation on drug response by co-relating gene expression or polymorphism with a drug’s efficacy or toxicity • It intends to identify individuals who are either more likely or less likely to respond to a drug, as well as those who require altered dose of .

Pharmacogenetics and Pharmacogenomics - Frontiers ~ Pharmacogenetics and Pharmacogenomics welcomes submissions of the following article types: Brief Research Report, Case Report, Clinical Trial, Correction, Data Report, Editorial, General Commentary, Hypothesis and Theory, Methods, Mini Review, Opinion, Original Research, Perspective, Review, Specialty Grand Challenge, Systematic Review and Technology and Code.

Pharmacogenomics - The Lancet ~ Genomic medicine, which uses DNA variation to individualise and improve human health, is the subject of this Series of papers. The idea that genetic variation can be used to individualise drug therapy—the topic addressed here—is often viewed as within reach for genomic medicine. We have reviewed general mechanisms underlying variability in drug action, the role of genetic variation in .

Pharmacogenetic Information in Clinical Guidelines: The ~ Pharmacogenetic Information in Clinical Guidelines: The European Perspective. Jesse J. Swen. Department of Clinical Pharmacy & Toxicology, Leiden University Medical Centre, Leiden, . among pharmacists and physicians show that these healthcare professionals have successfully adopted the concept of pharmacogenomics .